Natural Products

kahalalide F from ChemicalBook.com

Gavagnin, M., Mollo, E., Cimino, G. (2015) Is phototridachiahydropyrone a true natural product? Brazilian Journal of Pharmacognosy, 25 (6), pp. 588-591. [NP] [Cr]

Rasher, D.B., Stout, P.B., Engel, S., Shearer, T.L. , Kubanek, J., Hay,M.E. (2015) Marine and terrestrial herbivores display convergent chemical ecology despite 400 million years of independent evolution. Proceedings of the  National Academy of Sciences 112(39), pp. 12110 – 12115. [NP] [Tu]

Krug, P.J., Vendetti, J.E., Rodriguez, A.K., Retana, J.N., Hirano, Y.M., Trowbridge, C.D. (2013) Integrative species delimitation in photosynthetic sea slugs reveals twenty candidate species in three nominal taxa studied for drug discovery, plastid symbiosis or biological control. Molecular Phylogenetics and Evolution, 69 (3), pp. 1101-1119. Abstract [BC] [NH] [NP] [To]

Davis, J., Fricke, W.F., Hamann, M.T., Esquenazi, E., Dorrestein, P.C., Hill, R.T. (2013) Characterization of the bacterial community of the chemically defended Hawaiian sacoglossan Elysia rufescens. Applied and Environmental Microbiology, 79 (22), pp. 7073-7081. PDF [NP] [Ru]

Carbone, M., Muniain, C., Castelluccio, F., Iannicelli, O., Gavagnin, M.(2013) First chemical study of the sacoglossan Elysia patagonica: Isolation of a ?-pyrone propionate hydroperoxide Biochemical Systematics and Ecology, 49, pp. 172-175. Paywall [NP] [Pa]

Baumgartner, F.A., Motti, C.A., De Nys, R., Paul, N.A. (2009) Feeding preferences and host associations of specialist marine herbivores align with quantitative variation in seaweed secondary metabolites. Marine Ecology Progress Series, 396, pp. 1-12. PDF [F] [NP] [To]

Cutignano, A., Cimino, G., Villani, G., Fontana, A. (2009) Shaping the polypropionate biosynthesis in the solar-powered mollusc Elysia viridis. ChemBioChem, 10 (2), pp. 315-322. PDF [NP] [Vi]

Díaz-Marrero, A.R., Cueto, M., D’Croz, L., Darias, J. (2008) Validating an endoperoxide as a key intermediate in the biosynthesis of elysiapyrones. Organic Letters, 10 (14), pp. 3057-3060. PDF [NP] [Di]

Van Alstyne, K.L. (2008) The distribution of DMSP in green macroalgae from northern New Zealand, eastern Australia and southern Tasmania. Journal of the Marine Biological Association of the United Kingdom, 88 (4), pp. 799-805. PDF [F] [NP] [Ma]

Rao, K.V., Na, M., Cook, J.C., Peng, J., Matsumoto, R., Hamann, M.T. (2008) Kahalalides V-Y isolated from a Hawaiian collection of the sacoglossan mollusk Elysia rufescens. Journal of Natural Products, 71 (5), pp. 772-778. PDF [NP] [Ru]

Tilvi, S., Naik, C.G. (2007) Tandem mass spectrometry of kahalalides: Identification of two new cyclic depsipeptides, kahalalide R and S from Elysia grandifolia. Journal of Mass Spectrometry, 42 (1), pp. 70-80. PDF [NP] [Gr]

Faircloth, G., Cuevas, C. (2006) Kahalalide F and ES285: potent anticancer agents from marine molluscs. Progress in molecular and subcellular biology, 43, pp. 363-379. Abstract [NP] [Ru]

Ashour, M., Edrada, R., Ebel, R., Wray, V., Wätjen, W., Padmakumar, K., Müller, W.E.G., Lin, W.H., Proksch, P. (2006) Kahalalide derivatives from the Indian sacoglossan mollusk Elysia grandifolia. Journal of Natural Products, 69 (11), pp. 1547-1553. Abstract [NP] [Gr]

Ciavatta, M.L., Gresa, M.P.L., Gavagnin, M., Manzo, E., Mollo, E., D’Souza, L., Cimino, G. (2006) New caulerpenyne-derived metabolites of an Elysia sacoglossan from the South Indian coast. Molecules, 11 (10), pp. 808-816. Abstract (link to free PDF) [NP]

Gracia, C., Isidro-Llobet, A., Cruz, L.J., Acosta, G.A., Álvarez, M., Cuevas, C., Giralt, E., Albericio, F. (2006) Convergent approaches for the synthesis of the antitumoral peptide, Kahalalide F. study of orthogonal protecting groups. Journal of Organic Chemistry, 71 (19), pp. 7196-7204. PDF [NP] [Ru]

Jeffery, D.W., Perkins, M.V., White, J.M. (2005) Synthesis of an analogue of the marine polypropionate tridachiahydropyrone.  Organic Letters, 7 (3), pp. 407-409. PDF [NP] [Cr]

Cueto, M., D’Croz, L., Maté, J.L., San-Martín, A., Darias, J. (2005) Elysiapyrones from Elysia diomedea. Do such metabolites evidence an enzymatically assisted electrocyclization cascade for the biosynthesis of their bicyclo[4.2.0]octane core? Organic Letters, 7 (3), pp. 415-418. PDF [NP] [Di]

Marín, A., Ros, J. (2004) Chemical defenses in Sacoglossan Opisthobranchs: Taxonomic trends and evolutive implications [Defensas químicas en los opistobranquios sacoglosos: Tendencias taxonómicas e implicaciones evolutivas]. Scientia Marina, 68 (SUPPL 1), pp. 227-241. PDF [NH] [NP] [Ti] [Vi]

Giménez-Casalduero, F., Muniain, C., García-Charton, J.A. (2002) Elysia timida (Risso, 1818) (Gastropoda, Opisthobranchia): Relationship and feeding deterrence to a potential predator on the south-western Mediterranean coast. Marine Biology, 141 (6), pp. 1051-1057. PDF [NH] [NP] [Ti]

Jimeno, J.M. (2002) A clinical armamentarium of marine-derived anti-cancer compounds. Anti-Cancer Drugs, 13 (SUPPL. 1), pp. S15-S19. Abstract [NP] [Ru]

Nuijen, B., Bouma, M., Floriano, P., Manada, C., Rosing, H., Stokvis, E., Bosch, J.J.K.-V.D., Bult, A., Beijnen, J.H. (2001) Development of an HPLC method with UV detection for the pharmaceutical quality control of the novel marine anticancer agent kahalalide F. Journal of Liquid Chromatography and Related Technologies, 24 (20), pp. 3141-3155. Abstract [NP] [Ru]

Becerro, M.A., Goetz, G., Paul, V.J., Scheuer, P.J. (2001) Chemical defenses of the sacoglossan mollusk Elysia rufescens and its host alga Bryopsis sp. Journal of Chemical Ecology, 27 (11), pp. 2287-2299. Abstract [F] [NP] [Ru]

López-Macià, A., Jiménez, J.C., Royo, M., Giralt, E., Albericio, F. (2001) Synthesis and structure determination of kahalalide F. Journal of the American Chemical Society, 123 (46), pp. 11398-11401. PDF [NP] [Ru]

Fontana, A., Ciavatta, M.L., D’Souza, L., Mollo, E., Naik, C.G., Parameswaran, P.S., Wahidulla, S., Cimino, G. (2001) Selected chemo-ecological studies of marine opisthobranchs from Indian coasts. Journal of the Indian Institute of Science, 81 (4), pp. 403-415. PDF [NH] [NP]

Horgen, F.D., Delos Santos, D.B., Goetz, G., Sakamoto, B., Yukiko, K., Nagai, H., Scheuer, P.J. (2000) A new depsipeptide from the sacoglossan mollusk Elysia ornata and the green alga bryopsis species.  Journal of Natural Products, 63 (1), pp. 152-154. Abstract [NP] [Or]

Gavagnin M, Mollo E, Montanaro D, Ortea J, Cimino G (2000) Chemical studies of Caribbean sacoglossans: Dietary relationships with green algae and ecological implications. J Chem Ecol 26(7):1563–1578.

Bhosale, S.H., Jagtap, T.G., Naik, C.G. (1999) Antifungal activity of some marine organisms from India, against food spoilage Aspergillus strains. Mycopathologia, 147 (3), pp. 133-138. [NP] [Gr]

Gavagnin, M., Mollo, E., Castelluccio, F., Montanaro, Elysia RissoD., Ortea, J., Cimino, G. (1997) A novel dietary sesquiterpene from the marine sacoglossan Tridachia crispata.  Natural Product Letters, 10 (2), pp. 151-156. Abstract [NP] [Cr]

Gavagnin, M., Mollo, E., Cimino, G., Ortea, J. (1996) A new ?-dihydropyrone-propionate from the Caribbean sacoglossan Tridachia crispata. Tetrahedron Letters, 37 (24), pp. 4259-4262. Abstract [NP] [Cr]

Hay, M.E., Pawlik, J.R., Duffy, E., Fenical, W. (1989) Use of ingested algal diterpenoids by Elysia halimedae Macnae (Opisthobranchia : Ascoglossa) as antipredator defenses. Oecologoa 81:418-427 [NP] [Pu]

Paul, V.J. & van Alstyne, K.L. (1988) Use of ingested algal diterpenoids by Elysia halimedae Macnae (Opisthobranchia : Ascoglossa) as antipredator defenses.  J. Exp. Mar. Biol. Ecol. 119: 15 [NP] [Pu]

Ksebati, M.B., Schmitz, F.J. (1985) Tridachiapyrones: Propionate-derived metabolites from the sacoglossan mollusc Tridachia crispata. Journal of Organic Chemistry, 50 (26), pp. 5637-5642. Abstract [NP] [Cr]

Ireland, C., and Faulkner, D.J. (1981) The metabolites of the marine mollusk Tridachiella diomedea and Tridachia crispata. Tetrahedron 37 (suppl 1): 233-240 [NP] [Cl] [Di]

Ireland, C., and Scheuer, P.J. (1979) Photosynthetic marine molluscs: In vivo 14C incorporation into metabolites of the sacoglossan Placobranchus ocellatus Science 205: 922-923 [NP]

Ireland, C., Faulkner, D.J., Finer, J.S., Clardy, J. (1979) Crispatone, a metabolite of the opisthobranch mollusc Tridachia crispata [1]. Journal of the American Chemical Society, 101 (5), pp. 1275-1276. Scanned version [NP] [Cr]

Ireland, C., John Faulkner, D., Solheim, B.A., Clardy, J. (1978) Tridachione, a propionate-derived metabolite of the opisthobranch mollusc Tridachiella diomedea [22]. Journal of the American Chemical Society, 100 (3), pp. 1002-1003. Abstract [NP] [Di]

 

 

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